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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
O43396
USC-OGP 2-DE database
:
O43396
O43396
General information about the entry
View entry in simple text format
Entry name
TXNL1_HUMAN
Primary accession number
O43396
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Thioredoxin-like protein 1; AltName: Full=32 kDa thioredoxin-related protein;.
Gene name
Name=TXNL1
Synonyms=TRP32, TXL, TXNL
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-5
{PLATELET 4-5}
Homo sapiens (Human)
map experimental info
PLATELET_4-5
MAP LOCATIONS:
SPOT OGP-0124
:
pI=4.90; Mw=35873
SPOT OGP-0126
:
pI=5.00; Mw=35511
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0451
:
pI=5.03; Mw=35075
PLATELET_5-6
{PLATELET 5-6}
Homo sapiens (Human)
map experimental info
PLATELET_5-6
MAP LOCATIONS:
SPOT OGP-0733
:
pI=5.06; Mw=35872
Cross-references
UniProtKB/Swiss-Prot
O43396; TXNL1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
TXNL1_HUMAN
Primary accession number
O43396
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
March 15, 2017 (version 166)
Name and origin of the protein
Description
RecName: Full=Thioredoxin-like protein 1; AltName: Full=32 kDa thioredoxin-related protein;
Gene name
Name=TXNL1
Synonyms=TRP32, TXL, TXNL
Encoded on
Name=TXNL1; Synonyms=TRP32, TXL, TXNL
Keywords
3D-structure
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Disulfide bond
;
Electron transport
;
Nucleus
;
Phosphoprotein
;
Proteasome
;
Redox-active center
;
Reference proteome
;
Transport
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AF003938; AAC39599.1
; -; mRNA
EMBL
AF052659; AAC39898.1
; -; mRNA
EMBL
AF143897; AAF66676.1
; -; Genomic_DNA
EMBL
AF143890; AAF66676.1
; JOINED; Genomic_DNA
EMBL
AF143891; AAF66676.1
; JOINED; Genomic_DNA
EMBL
AF143892; AAF66676.1
; JOINED; Genomic_DNA
EMBL
AF143893; AAF66676.1
; JOINED; Genomic_DNA
EMBL
AF143894; AAF66676.1
; JOINED; Genomic_DNA
EMBL
AF143895; AAF66676.1
; JOINED; Genomic_DNA
EMBL
AF143896; AAF66676.1
; JOINED; Genomic_DNA
EMBL
AF051896; AAC05830.1
; -; mRNA
EMBL
BC001156; AAH01156.1
; -; mRNA
CCDS
CCDS11961.1; -
; .
PIR
JC5938; JC5938
; .
RefSeq
NP_004777.1; NM_004786.2
; .
RefSeq
XP_016881582.1; XM_017026093.1
; .
UniGene
Hs.114412; -
; .
PDB
1GH2; X-ray
; 2.22 A; A=2-108
PDB
1WWY; NMR
; -; A=122-279
PDBsum
1GH2; -
; .
PDBsum
1WWY; -
; .
ProteinModelPortal
O43396; -
; .
SMR
O43396; -
; .
BioGrid
114755; 59
; .
IntAct
O43396; 9
; .
MINT
MINT-5005836; -
; .
STRING
9606.ENSP00000217515; -
; .
iPTMnet
O43396; -
; .
PhosphoSitePlus
O43396; -
; .
BioMuta
TXNL1; -
; .
OGP
O43396; -
; .
REPRODUCTION-2DPAGE
IPI00305692; -
; .
EPD
O43396; -
; .
PaxDb
O43396; -
; .
PeptideAtlas
O43396; -
; .
PRIDE
O43396; -
; .
TopDownProteomics
O43396; -
; .
DNASU
9352; -
; .
Ensembl
ENST00000217515; ENSP00000217515
; ENSG00000091164; .
Ensembl
ENST00000590954; ENSP00000464918
; ENSG00000091164; .
GeneID
9352; -
; .
KEGG
hsa:9352; -
; .
CTD
9352; -
; .
DisGeNET
9352; -
; .
GeneCards
TXNL1; -
; .
HGNC
HGNC:12436; TXNL1
; .
HPA
CAB016446; -
; .
HPA
HPA002828; -
; .
HPA
HPA002829; -
; .
MIM
603049; gene
; .
neXtProt
NX_O43396; -
; .
OpenTargets
ENSG00000091164; -
; .
PharmGKB
PA134967488; -
; .
eggNOG
KOG0908; Eukaryota
; .
eggNOG
ENOG410YQ2G; LUCA
; .
GeneTree
ENSGT00530000063008; -
; .
HOGENOM
HOG000189802; -
; .
HOVERGEN
HBG055982; -
; .
InParanoid
O43396; -
; .
OMA
PIFEMFP; -
; .
OrthoDB
EOG091G0G71; -
; .
PhylomeDB
O43396; -
; .
TreeFam
TF314399; -
; .
ChiTaRS
TXNL1; human
; .
EvolutionaryTrace
O43396; -
; .
GeneWiki
TXNL1; -
; .
GenomeRNAi
9352; -
; .
PRO
PR:O43396; -
; .
Proteomes
UP000005640; Chromosome 18
; .
Bgee
ENSG00000091164; -
; .
CleanEx
HS_TXNL1; -
; .
ExpressionAtlas
O43396; baseline and differential
; .
Genevisible
O43396; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005634; C:nucleus
; IEA:UniProtKB-SubCell; .
GO
GO:0000502; C:proteasome complex
; IEA:UniProtKB-KW; .
GO
GO:0015036; F:disulfide oxidoreductase activity
; IDA:UniProtKB; .
GO
GO:0016671; F:oxidoreductase activity
; acting on a sulfur group of donors; disulfide as acceptor
IBA:GO_Central
.
GO
GO:0015035; F:protein disulfide oxidoreductase activity
; IBA:GO_Central; .
GO
GO:0047134; F:protein-disulfide reductase activity
; IBA:GO_Central; .
GO
GO:0004791; F:thioredoxin-disulfide reductase activity
; IBA:GO_Central; .
GO
GO:0045454; P:cell redox homeostasis
; IBA:GO_Central; .
GO
GO:0034599; P:cellular response to oxidative stress
; IBA:GO_Central; .
Gene3D
2.60.120.470; -
; 1; .
Gene3D
3.40.30.10; -
; 1; .
InterPro
IPR008979; Galactose-bd-like
; .
InterPro
IPR010400; PITH_dom
; .
InterPro
IPR012336; Thioredoxin-like_fold
; .
InterPro
IPR017937; Thioredoxin_CS
; .
InterPro
IPR013766; Thioredoxin_domain
; .
Pfam
PF06201; PITH
; 1; .
Pfam
PF00085; Thioredoxin
; 1; .
SUPFAM
SSF49785; SSF49785
; 1; .
SUPFAM
SSF52833; SSF52833
; 1; .
PROSITE
PS51532; PITH
; 1; .
PROSITE
PS00194; THIOREDOXIN_1
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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